We make Vine Tea Extract 98% Dihydromyricetin at Xi'an DN Biology Co., Ltd. This is a pharmaceutical-grade flavonoid compound that comes from Ampelopsis grossedentata. Since 2010, our facility has been processing up to 3,000 tons of material every year using advanced extraction systems that include 4 large vessels (6 m³ each) and spray-drying technology that is built in. Our ultra-high purity DHM is tested using HPLC to make sure it has a dihydromyricetin level of at least 98%, with no more than 3% moisture, 1% ash, or 5ppm heavy metals. The light yellow-white powder (80–100 mesh) is certified by ISO 22000, GMP, HACCP, Halal, and Kosher. It has consistent bioactivity for liver protection, hangover recovery, and metabolic health formulations. You can get up to 100 tons of stock, and production can be done quickly (7–15 days) for your B2B needs.
The product is the purest that can be bought commercially for use in nutraceutical and pharmaceutical products. Unlike lower-grade extracts that still have tannins and polysaccharides in them, our 98% DHM isolate doesn't change the taste of finished goods and doesn't cause problems with precipitation.
The molecule structure (C15H12O8, CAS 27200-12-0) has many hydroxyl groups that are very good at getting rid of reactive oxygen species (ROS). Our controlled 80–100 mesh particle size and less than 3% moisture content make it possible for you to predict how quickly your formulations will dissolve.
Our ethanol-water purification method makes sure that any solvent residues meet USP <467> requirements. This pharmaceutical-grade method ensures clean-label status, which meets the growing demand from customers for health supplement ingredient profiles that are easy to understand.
| Parameter | Specification |
|---|---|
| Active Ingredient | Dihydromyricetin (DHM) ≥98% |
| Appearance | Light yellow-white powder |
| Mesh Size | 80-100 mesh |
| Loss on Drying | ≤3% |
| Ash Content | ≤1% |
| Heavy Metals | ≤5 ppm |
| Lead (Pb) | <0.5 ppm |
| Arsenic (As) | <0.5 ppm |
| Extraction Solvent | Ethanol-water |
| Melting Point | 245°C–248°C |
| Total Plate Count | <1000 cfu/g |
| Pathogen Testing | Negative for E. coli & Salmonella |
Alcohol Metabolism and Getting Over a Hangover
By increasing the activity of ADH and ALDH enzymes, our product speeds up the breakdown of acetaldehyde. You can put it in pills, fizzy tablets, or ready-to-drink shots that are aimed at the functional beverage market. According to clinical study, DHM works as a GABAA receptor antagonist to help lower the sedative effects of alcohol while also supporting the liver's detoxification pathways.
Hepatoprotective Supplement Formulations
Use our 98% pure extract to make clinical-grade liver support goods. Because it is an antioxidant, it lowers lipid peroxidation and deals with markers of non-alcoholic fatty liver disease (NAFLD). The pharmaceutical-grade purity makes sure that therapeutic doses are always the same.
Nutrition for Sports and Metabolic Health
DHM can improve insulin sensitivity and fight oxidative stress caused by exercise, which can help your functional food lines. The 98% content stops polyphenolic precipitation, which happens with less pure botanicals. This keeps drinks clear and the shelf life stable.

Advanced Production Infrastructure
We run 4 extraction vessels, each with a capacity of 6 m³, and 3 integrated concentration systems. Under ISO 9001 and FSSC 22000 rules, our facility does decolorization, vacuum drying, spray drying, and stratification. This kind of vertical integration makes your supply chain more stable than anyone else's.
Tough Quality Control
C18 column chromatography is used to check each run using HPLC at 290nm. We test for heavy metals with ICP-MS and over 400 pesticides with GC-MS/MS, which meets EU and USDA organic guidelines. We always support testing by a third-party lab, and we offer free samples before shipping.
Service Options for OEM and ODM
No matter if you need unique formulations, certain particle sizes, or branded packaging, our R&D team can help you from the idea stage all the way through to the final product. We can meet your needs because we have up to 100 tons in stock and wait times of 7 to 15 days.
Global Compliance & Traceability
With our full-chain traceability system, we can connect each batch to the planting base where it came from. Certifications include Halal, Kosher, FDA compliance, and multiple ISO standards, which make sure that the goods go through customs checks easily all over the world. We offer DDP shipping and factory checks in person.

We use a five-part quality strategy for Vine Tea Extract 98% Dihydromyricetin:
Purity Verification: HPLC tests show that there is at least 98% DHM content, and UV measurement is very accurate.
To make sure the solvent is safe, ethanol residue tracking meets the standards set by the International Pharmacopoeia.
Heavy Metal Screening: ICP-MS tests were done to find sub-ppm levels of lead, arsenic, cadmium, and mercury.
Analysis of Pesticides: Full GC-MS/MS panels include more than 400 compounds that are harmful to agriculture.
Microbiological Integrity: The total plate counts stay below 1000 cfu/g, and there is no tolerance for pathogens. This means that the dietary supplement meets safety standards.
Our separate lab, which has HPLC, GC, UV-Vis, and moisture analyzers, makes sure that every shipment meets your needs. Certificates of Analysis, third-party test reports, and full traceability records are all part of documentation packages.

Food-grade aluminium foil bags with desiccant are used to pack the goods, and they are sealed inside fibre drums that weigh 25 kg net. For foreign shipping, bigger bulk orders come in boxes with two layers of PE bags.
All of the packaging meets FDA standards for food handling. Labels have production dates, batch numbers, and QR codes that lead to digital Certificates of Analysis. For items that are already in stock, we ship them within 7 days of receiving payment, either by air freight, sea freight, or DDP.
Q: What are the main benefits of the product?
A: DHM supports liver function, accelerates alcohol metabolism, and provides antioxidant protection. Users report improved energy levels, enhanced immune response, and anti-aging effects due to its ROS-scavenging properties.
Q: Where does your dihydromyricetin originate?
A: We source from controlled cultivation bases in southern China, with options for Himalayan highland varieties. All raw materials undergo identity verification before processing.
Q: What product forms work best with this extract?
A: The 98% powder integrates seamlessly into hard capsules, tablets, liquid concentrates, and beverage blends. Its high purity prevents cloudiness in aqueous solutions.
Q: How stable is DHM during storage?
A: When stored in sealed containers below 25°C with <5% moisture, our extract maintains potency for 24 months. Avoid strong alkaline environments that may degrade the compound.
Q: Can you customize extraction ratios or concentrations?
A: Yes. Our OEM services include custom DHM concentrations, particle size adjustments, and formula development based on your target application.

Ready to elevate your formulations with Vine Tea Extract 98% Dihydromyricetin? Reach out today at Info@dnbiology.com to request your no-obligation sample pack and detailed product documentation.